Ampicillin Dry Suspension 125MG / 5ML 60ML Oral Suspension Drugs

Ampicillin For Oral Suspension Drugs 125MG / 5ML 60ML

COMPOSITION:

Each 5 ML syrup contains: Ampicillin 125MG

PHARMACOLOGICAL ACTION:

Ampicillin is bactericidal with a broad spectrum of activity in vitro against Gram-positive non-penicillinase producing staphylococci, haemolytic and non-haemolytic streptococci, Diplococcus pneumoniae, Clostridia

sp. and Streptococcus faecalis. Also the Gram-negative cocci, Neissera sp., H. influenzae, E. coli, Proteus mirabalis and many strains of brucellae, salmonellae and shigellae. It has been determined that certain organisms which were previously sensitive are already showing resistance.

INDICATIONS:

Indicated in infections due to susceptible organisms.

CONTRA-INDICATIONS:

Penrite should not be given to patients known to be sensitive to penicillin or in the neonatal period, to babies born of hypersensitive mothers. Penrite should not be given to patients with infectious mononucleosis since they are susceptible to ampicillin-induced skin rashes.

DOSAGE AND DIRECTIONS FOR USE:
Adults: 250 mg to 750 mg every six hours.
Children:

Much higher doses (up to 12 g daily in adults) may be given safely. Oral preparations should be taken half an hour before meals.

Directions for reconstituting suspension :

Add 75 mL distilled water to dry powder in the bottle and shake well.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:

If symptoms due to overgrowth of non-susceptible organisms (Aerobacter aerogenes, Pseudomonas, Candida, etc.), appear, the medicine should be discontinued and specific or supportive therapy instituted. Side effects are usually mild, transitory and are similar to those found with other penicillins. Transient diarrhoea, nausea, heartburn and pruritis ani may occur. When ampicillin is administered to a hypersensitive patient allergic reactions may occur.
Urticaria and skin rashes are common. Exfoliative dermatitis, eosinophilia, angio neurotic oedema, fever and swollen joints may occur. Severe allergic reactions which may be fatal occur. These reactions are more common after a previous course of treatment. The onset of the symptoms varies, it may occur within a few hours or days of the onset of the treatment or not until therapy with a penicillin derivative is resumed on a subsequent occasion.
Should a serious anaphylactic reaction occur, Penrite should be discontinued and the patient treated with the usual agents (adrenalin, corticosteroids and antihistamines). Reduced doses may be required in patients with impaired renal function. In cases of ampicillin treatment of mononucleosis, a rash usually appears.

STORAGE INSTRUCTIONS:

Keep in a dry place below 25°C.
Keep out of reach of children.
Potency of the reconstituted suspension will be maintained for one week at a temperature below 25°C and two weeks at 2-8°C.