HEALEY PHARMA (UK) LIMITED
HEALEY PHARMA (UK) LIMITED
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DOXYCYCLINE 200 MG Capsules
COMPOSITION:
Each capsule contains: Doxycycline hyclate equivalent to 200 mg doxycycline.
PHARMACOLOGICAL ACTION:
Doxycycline is bacteriostatic against susceptible strains of a wide range of Gram-positive and Gram-negative bacteria.
Doxycycline is widely distributed into pleural and peritoneal fluid, saliva, semen and prostatic fluid. It passes the placental barrier readily and is also present in the milk of lactating patients. It is concentrated by the liver and excreted, by way of the bile, into the intestine from which it is partially reabsorbed. Conventional doses of doxycycline are not excreted in the urine to the same extent as other tetracyclines and it does not accumulate significantly in the blood of patients with renal failure. Extrarenal infections in individuals may be treated with doxycycline when indicated. Doxycycline is excreted in the faeces, largely as an inactive conjugate or chelate.
INDICATIONS:
For the treatment of Brucellosis, trachoma, urinary tract infections, sensitive gonococcal infections.
CONTRA-INDICATIONS:
Pregnancy and lactation and in young children. Sensitivity to any tetracycline. As preparations containing iron, aluminium, calcium or magnesium decrease the absorption of doxycycline, do not give to patients receiving antacid therapy, milk or calcium containing foods. Potentially hepatotoxic medicine should not be given with doxycycline.
WARNINGS:
Use with care in liver function impairment. Symptoms of myasthenia gravis may be aggravated. Photosensitivity may occur.
DOSAGE AND DIRECTIONS FOR USE:
Doxycycline should be taken one hour before meals or two hours after meals.
Adults: one capsule every 24 hours.
INTERACTIONS:
Absorption of CYCLIDOX EC is diminished by milk, alkalis, aluminium hydroxide and other di- and trivalent cations such as calcium, iron and magnesium if they are given concomitantly. Doses of anticoagulants may need to be reduced if given concomitantly with CYCLIDOX EC. Doxycycline may decrease the efficacy of oral contraceptives. Penicillin should not be given concomitantly with CYCLIDOX EC as antagonism in action may occur.
STORAGE INSTRUCTIONS:
Store below 25°C and protect from light.
KEEP OUT OF REACH OF CHILDREN.