HEALEY PHARMA (UK) LIMITED
HEALEY PHARMA (UK) LIMITED
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Metronidazole Tablets 250MG 500MG Antibiotic 10*10's / Box 100's / Bottle
METRONIDAZOLE 250 MG Tablets
COMPOSITION.
Each metronidazole 250 mg Tablet contains metronidazole 250 mg.
PHARMACOLOGICAL ACTION:
Metronidazole is an anti- protozoal agent effective against Trichomonas vaginalis, Entamoeba histolytica and in giardiasis.
Metronidazole is useful for the treatment of infections caused by various anaerobic bacteria,
particularly Bacteroides fragilis.
INDICATIONS:
Urogenital trichomoniasis;Amoebiasis;Giardiasis;Ulcerative gingivitis (Vincent's infection)
Infections caused by anaerobic bacteria, especially Bacteroides fragilis.
As a prophylactic in postsurgical abdominal and pelvic infections.
CONTRA-INDICATIONS:
Metronidazole tablets should not be used in patients with blood dyscrasias or with active disease of the
central nervous system, or during pregnancy or lactation.
WARNINGS:
Pseudomembranous colitis has been reported with the use of metronidazole.
DOSAGE AND DIRECTIONS FOR USE:
Tablets should preferably be swallowed whole with half a glassful of water during or after meals.
Anaerobic infections
Adults: 1g to 1.5g/day
Children: 20 to 30mg/kg/day
Giardiasis
Adults and children over 15years: 0.75mg to 1g/day
Trichomonas vaginalis
500mg twice daily for 10 days
Partner must be treated simultaneously even she/he does not demonstrate any clinical signs interactive
with other days.
Metrozem should not be used with any medicines containing alcohol.
SIDE EFFECTS AND SPECIAL PRECAUTIONS:
The side-effects of metronidazole tablets include gastro-intestinal discomfort, anorexia, nausea, coated tongue, dryness of the mouth and an unpleasant taste,
headaches and skin rashes and, less frequently, vertigo, depression, insomnia, drowsiness, urethral
discomfort and darkening of the urine. There may be a temporary decrease in the total white cell count.
Metronidazole tablets should be avoided during pregnancy. When given in conjunction with alcohol,
metronidazole tablets may produce a disulfiram-like reaction. Metronidazole tablets enhance the anticoagulant effect of warfarin.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Early gastric lavage is recommended.
STORAGE INSTRUCTIONS:
Store below 25°C. Protect from light. Keep out of reach of children.